CD44 antibody (C-Term)

Catalog No. ABIN2788656

This Rabbit Polyclonal antibody specifically detects CD44 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Cow, Horse and Guinea Pig.

Quick Overview for CD44 antibody (C-Term) (ABIN2788656)

Target: CD44

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD44 Antibody

Binding Specificity: C-Term

Sequence: SGNGAVEDRK PSGLNGEASK SQEMVHLVNK ESSETPDQFM TADETRNLQN

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CD44. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CD44

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 361 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Alias Symbols: CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1, HUTCH-I
Protein Interaction Partner: UBC, NF2, NEDD8, BAG1, DPP8, VHL, SRC, ANK1, ATF2, FMNL1, IQGAP1, SLC3A2, STAT3, ITGB1, FLOT2, EP300, CAV1, PRKCZ, ELAVL1, ARHGEF12, ARHGEF1, PKN1, DMP1, HMMR, TIAM1, ERBB4, VAV2, GARS, TGFBR2, TGFBR1, CD4, MMP7, SRGN, SPP1, LCK, IGFBP3, CD74, FYN, FGF2,
Protein Size: 361

Molecular Weight: 40 kDa

Gene ID: 960

NCBI Accession: NM_001001391, NP_001001391

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling